JNTU HYDERABAD III.B.PHARMACY II SEMESTER REGULAR EXAMINATIONS MAY 2010 PHARMACEUTICAL JURISPRUDENCE
1. What are Ethics and code of Ethics? Describe the role of Pharmacist in relation to his Job, Profession and Trade.
2. Give an account on the construction, functions and powers Council of India and State Pharmacy Council.
3. a) Explain the qualifications, duties and Procedures of inspection by Drug Inspector
b) Write the constitution of Drug Consultative Committee
4. a) Define Narcotic and Psychotropic substance. Explain the powers of central government to permit, control and regulate Narcotic and Psychotropic substances as per the act.
b) Write a note on Illicit traffic?
5. Discuss in detail about
a) Manufacture of preparations outside the bond
b) Warehousing of Alcoholic preparations
6. Write a note on
a) Drug Price Control Order
b) Factories Act 1948
7. a) Define License. Explain different types of licenses.
b) Discuss the manufacturing of drugs specified in schedule C, C1 and X
8. a) Discuss about prohibited advertisements and related offences and
penalties
b) Write a note on Indian Patents Act 1970
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JNTU HYDERABAD III. B. PHARMACY II SEMESTER REGULAR EXAMINATIONS MAY 2010 PHARMACOLOGY-II
1.a) Classify antihypertensives with suitable examples and discuss the mechanism of action and therapeutic uses of vasodilators.
b) Write a short note on plasma volume expanders.
2. Classify drugs used in angina. Discuss the pharmacology of calcium channel blockers.
3. What are arrhythmias? Discuss the pharmacology of Class I antiarrhythmic drugs.
4. a) Discuss in detail about oral anticoagulants.
b) Write in detail about Iron.
5. Classify diuretics. Write the detailed pharmacology of Frusemide.
6. a) Classify antihistaminics with suitable examples. Discuss their therapeutic uses and adverse effects.
b) Write a short note on 5HT receptors, their agonists and antagonists.
7. a) Write in detail about physiological role of Angiotensin and add a note on angiotensin antagonists.
b) Discuss the synthesis, metabolism and physiological role of Bradykinin.
8. a) Classify antiasthmatic agents with suitable examples. Discuss the pharmacology of bronchodilators.
b) Write a short note on antitussives.
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JNTU HYDERABAD III. B. PHARMACY II SEMESTER REGULAR EXAMINATIONS MAY 2010 CHEMISTRY OF NATURAL DRUGS
1.(a) How will you differentiate the following by hydrolysis, explain with
chemical reaction and structure.
i) Atropine
ii) Hyoscyamine
iii) Hyosine
(b) Differentiate tropine and pseudotropine.
2. Classify ergot alkaloids and give structures, hydrolytic products and therapeutic uses of any four ergot alkaloids?
3. Explain the following.
a. Isoprene rule
b.Gem-dialkyl rule
c.Ozonolysis of terpenes
d.Stereochemistry of citral
4. Convert the following
a. Cavone to cavacrol
b. Menthol to thymol
c. Borneol to camphor
d. Camphor to borneol
5. Write on the following
a. Numbering of Bile acids, cholesterol, estrone, diels hydrocarbon
b. Synthesis of progesterone from diosgenin and cholesterol
6. Write detailed note on cardiac glycosides and mention MOA, toxicity and
thearapeutic uses?
7. Classify steroidal hormones and give brief note on the following
a. Contraceptive agents
b. Inter-conversion of estrogens
8. Write an account on
a) Insulin b) Cortisone c) Glucagon d) Thyroxine
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JNTU HYDERABAD IV B. Pharmacy I Semester Regular Examinations, January 2010 PHARMACOLOGY-Ill
1. Discuss in detail about the pharmacology of Proton pump inhibitors.
2. What are Penicillins? Write the mechanism of action, general toxicities and
therapeutic uses of Penicillins.
3. Write the mechanism of action and therapeutic uses and toxicities of
Chioramphenicol.
4. Define Antitubercular drugs. Explain in detail about any two second line
antitubercular drugs.
5.a) What are antiviral drugs ? Classify them
b) Write the mechanism of action, adverse effects, therapeutic uses and
pharmacokinetics of Acyclovir
6. Explain in detail about the antimetabolites used to treat cancer.
7. Explain the symptoms, mechanism and treatment of:
a) Barbiturate poisoning
b) Atropine poisoning.
8. Explain in detail about the different bioassay methods.
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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD I.Year B. Pharmacy Regular Examinations May/June 2010 ENGLISH LANGUAGE COMMUNICATION SKILLS
1. How does R.K. Laxman try to expose the middle class mentality in the story The Gold Frame?
2. How does Richard Selzer in his essay Save Your Liver elucidate the importance of saving the liver from diseases?
3. “Water plays the leading role in the drama of our life on the surface of our planet”- Explain
4. (a) How did Kalpana struggle to get selection as a member of NASA?
(b) Describe her first voyage aboard the Columbia Shuttle.
5. “When one loves one’s Art no service seems too hard”- Bring out the implications with reference to the story A Service of Love.
6. (a) What is the significance of the World Press Freedom Day observed on 3rd May?
(b) Why was this day chosen as the World Press Freedom day?
7. A textile company is thinking of extending its operations in Chennai. You have been asked to prepare a report on the suitability of Chennai for this. Prepare a report on the economic and social suitability of the city.
8. (a) Fill in the blanks with appropriate verb forms.
i)If he had invited me, I (attend) the function.
ii) She met with an accident while she (cross) the road.
iii) Don’t disturb me. I (do) my homework.
iv) She (suffer) from fever for a week.
(b) Fill in the blanks by choosing the appropriate word from the brackets
i)Go up the (stairs/stares) and her office is on the right.
ii) The (fir/fur) trees on the upper slope of the mountain were covered in snow.
iii) Coffee (beans/beens) are the seeds of the coffee tree.
iv) They pulled out of the deal at the last minute leaving us (hi/high) and dry.
(c) Supply one word substitute for each of the following.
i)The study of birds.
ii) A number of stars grouped together.
iii) That which cannot be read.
iv) The house of an Eskimo
(d) Correct the following sentences.
i)Not only the soldiers but also their captain have been captured.
ii) The house is belonging to her.
iii) She looks forward to help me.
iv) I shall call on you when the doctor will be ready.
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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD I.Year B. Pharmacy Regular Examinations May/June 2010 ANATOMY, PHYSIOLOGY AND HEALTH EDUCATION
1. Describe the anatomy of Elementary tissues of the human body?
2. Classify the joints? Describe the types of movements at joints?
3. Explain the blood groups and their significance?
4. Describe the lymphatic system of man?
5. What is Cardiac cycle? Explain the mechanism?
6. Define disease? Explain disease causing agents and prevention of disease?
7. What is shock? Describe the methods to prevent it?
8. Explain the causative agents, modes of transmission and prevention of the following diseases?
a) Influenza
b) Tuberculosis
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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD I.Year B. Pharmacy Regular Examinations May/June 2010PHARMACEUTICAL ORGANIC CHEMISTRY-I
1. a) Explain tetrahedral and trigonal hybridization.
b) Explain the following terms
i) Bond length
ii) Bond angle.
iii) Dipole movement.
iv) Hydrogen bonding.
2. a) Define isomerism and list different types of isomerism with examples.
b) Explain the stabilities of cycloalkanes using bayers strain theory .
i) 2, 2, 4- trimethyl pentane
ii) Ethyl ethanoate
3. a) Explain Friedel-Crafts alkylation and Friedel-Crafts acylation reactions of benzene.
b) Explain the electrophilic substitution reactions of naphthalene.
4. Define nucleophilic substitution reaction and explain reaction mechanism of SN1 and SN2
reaction.
5 a) Describe Zeisel method and give its significance.
b) Define rearrangement reaction and explain Fries rearrangement reaction.
6. a) Give an comprehensive account on oxidative reactions of carbonyl compounds.
b) Explain the following reaction with its mechanism
i) Clemmensen reduction
ii) Wolff- kishner reduction.
7. a) Explain Hell- Volhard- Zelinsky reaction.
b) Explain about Hofmann’s degradation of amides.
8. a) Explain about Hinsberg method of amine separation.
b) Explain the following reactions
i) Sandmeyer reaction
ii) Gattermann reaction
iii) Gabriel’s phthalamide synthesis.
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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD I.Year B. Pharmacy Regular Examinations May/June 2010 PHARMACEUTICAL INORGANIC CHEMISTRY
1. a) Discuss the significance of quality control test in pharmaceutical industry.
b) Explain the importance of Loss on ignition with suitable examples.
2. a) Give a note on haemodialysis fluids.
b) Write the preparation, assay principle and uses of
i) Dibasic calcium phosphate.
ii) Calcium gluconate.
3 a) Explain the preparation , assay principal and uses of Calcium carbonate and Sodium acid
Phosphate.
b) Define and enlist adsorbants?
4. a) Define and enlist Haematinics.
b) Give the method of preparation, assay principal and therapeutic uses of Ferric ammonium
citrate.
c) Explain how iodine extracted from kelp?
5. a) Define and classify inorganic expectorants.
b) Explain the principle and procedure involved in the assay of ammonium chloride and Copper
sulphate.
6. a) Explain the preparation and uses of the following
i) Yellow mercuric oxide.
ii) Zinc oxide.
iii) Boric acid.
iv) Bismuth subcarbonate.
b) Write about the anti-infective role of iodine preparations.
7. a) Explain the pharmaceutical importance of dental products.
b) Give a note on Mouth washes.
c) Write the preparation, properties and pharmaceutical uses of
i) Sodium fluoride.
ii) Sodium meta phosphate.
8. a) Write a assay of plaster of paris and barium sulphate
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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD I.Year B. Pharmacy Regular Examinations May/June 2010 DISPENSING AND HOSPITAL PHARMACY
1. a) Write about the role of pharmacist in community health care and education
b)Define an isotonic solution . Write about the importance of isotonicity in pharmacy
2. What is incompatibility? Write a note on physical incompatibility with examples.
3. Write a note on the following:
a) Idiosyncratic cases
b) Role of pharmacy and therapeutic committee in drug safety and adverse drug reactions
4. a) Write about distribution of drugs to out-patients
b) Distinguish between lotions and liniments
5. Define posology. Write about the various factors which influence dose of the drug
6. a) Define prescription. Write about different parts of prescription.
b) Define an emulsion. Write about various methods of preparation of emulsions.
7. Write a short note on the following:
a) Patient counseling.
b) Soft liquid extracts.
c) Responsibilities of hospital pharmacist.
8. a) Write about the functions of drug information centre.
b) Define an ointment. Discuss about trituration method used for preparation of ointments.
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JNTU HYDERABAD,II -II REGULAR EXAMINATION, MAY 2010 ENVIRONMENTAL SCIENCE
CODE NO:R7305
1.What is environment ? Give a detailed account of the structure of earth.Describe the potential grey areas where research can be carried on ?
2.What do mean by biomass energy ? What are its uses ? Discuss limitations in producing this enregy.
3.Write short note on the following
a.Ex-situ conservation
b.In-situ conservation
c.Biodiversity loss
4.'All aspects of production in ecosystems are a subject matter of productivity in ecosystems'.Discuss.
5.Discuss some of the programmes which have been launched for scientific management and careful use of fragile ecosystems.
6.Explain nuclear hazards and its effects.
7.Define consumerism.what measures would you suggest in order to eliminate waste product and save natural resources.
8.Highlight something on the wild life protection Act.Give reasons for the enactment of such act.
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JNTU HYDERABAD,II-II REGULAR EXAMINATION,MAY 2010 PHARMACEUTICAL UNIT OPERATIONS-II CODE NO:R7301
1.a )Explain Fourier's law of conduction of heat through a metal wall.
b) Write about compound resistance in series.
2. Explain:
a)Theory of Evaporation
b)Material balances in evaporation.
c)Energy balance in evaporation.
3.a)Classify distillation methods.
b)Write about simple distillation method and construction and working of simple distillation,apparatus.
4.a)A rotary dryer was used to dry 35,000 kg/hr of a wet drug containing 5% w/w of water to a water content of 0.2% w/w. Calculate the weight of water removed during the drying operation per hour.
b)A batch dryer removes water from a solid materialat the rate of 30 lb/hr during constant Rate period.Under the operating conditions the critical moisture content is 0.5lb of water/lb of dry solid and the equilibrium moisture content is 0.04lb of water/lb of dry solid.The curve of drying air vs moisture content may be assumed as a straight line during the entire falling rate period if 300lb of dry solid containing 200lb of water enters the dryer.How long will be the total drying time period if the final product contains 0.08lb of water/lb of dry solid?
5.a)Describe the milling equipment with the help of neat labeled diagram that uses the principle of shear & impact.
b)Explain the theories related to the size reduction of powder.
6.a) How can we estimate the degree of mixing.Explain.
b) Give the stastistical evaluation procedure for mixin g of powders.
7.a)What are different motions of particles during size separation.Explain them in detail.
b)Explain brushing method.
8.Write notes on the following:
a)Thermocouple
b)Resistance thermometers
c)Filled-in-thermometers
d)Bimetal thermometers.
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JNTU HYDERABAD,II-II REGULAR EXAMINATION,MAY 2010 PHARMACEUTICAL ANALYSIS-I
CODE NO:R7302
1.what are the various recommendations of a "Pharmaceutical analyst" on "rejecting an observation" for analytical results.
2.Explain the following
a) Precipitation reactions governing "Argentometric methods"
b)Various cardinal parameters required for a feasible argentometric analysis.
3.How does 'Residual titration method'help in the Complexometric titrations ? Elaborate the assay of following drugs
a)Potassium alum.
b)Bismuth sub carbonate
c)Aluminium glycinate
d) Dried Aluminium hydroxide.
4.Give the principle,construction and working of a polarography apparatus?
5.a)Give the various applications of Fluorescence and Phosphorescence.
b)Write about different types of source and manochromators in Fluorescence and Phosphorescence.
6.a) Explain instrumentation in Nephelometry and Turbidometry.
b)What are Turbidometric titrations?Explain.
7.Describe the principle ,construction and working of polarimeter.
8.Give an account of
a)Comparision of GC and HPLC.
b)Derivatisation techniques in GC and HPLC.
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JNTU HYDERABAD,II-II REGULAR EXAMINATION,MAY 2010 PHARMACOGNOSY-I CODE NO:R7303
1.Define pharmacognosy.Write in brief history and relationship with various allied sciences.
2.Enumerate the drug discovery based on a plant sources by giving suitable examples.
3.Deefine the following terms in therapeutic classification with examples:
a)Alkaloids
b)Glycosides.
c)Tannins
d)Resins.
4.Write a note on the following:
a)Asexual method of cultivation
b)Soil Fertility.
5.Explain the role of Cytolinins and Gibberelins in the production of secondary metabolites.
6.Describe the detailrd pharmacognostic study of Honey.
7.Define Lip ids. Classify them with suitable examples.Write the Biological source,chemical constituents and uses of
a) Bees wax
b) Lard.
8.Write the Biological source,chemical constituents and uses of
a)Tulsi.
b)Mentha
c)Coriander
d)Lemon grass oil.
